Examples for "degenerative changes in central nervous system"
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Background: AD is the most frequent neurodegenerativedisease, severely impacting our society.
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Summary: Integrative approaches to selective vulnerability may help clarify neurodegenerativedisease pathogenesis.
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ALS is a lethal neurodegenerativedisease wherein the diagnosis is often delayed.
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Spinal muscular atrophy is a neurodegenerativedisease that requires multidisciplinary medical care.
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Parkinson's is an incurable neurodegenerativedisease that affects 1 million Americans.
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Here, we analyzed 189 children with rareneurodegenerativedisease for carrying the T-allele by polymerase chain reaction-restriction fragment length polymorphism.
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Background: Previous studies raise the possibility that antioxidants protect against neurodegenerativediseases.
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Methods: It is a cross-sectional study with 44 patients with neurodegenerativediseases.
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Hypertension is a common age-related disease, along with vascular and neurodegenerativediseases.
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Such variability is elevated in neurodegenerativediseases or following traumatic brain injury.
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Memory decline during aging or accompanying neurodegenerativediseases, represents a major health problem.
Uso de neurodegeneration em inglês
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However, the mechanism by which TDP-43 mutations lead to neurodegeneration is unclear.
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There is urgent need to overcome such deleterious effects of age-related neurodegeneration.
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This study aimed to investigate the mechanisms underlying HCV core protein-mediated neurodegeneration.
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The mechanism of neurodegeneration caused by beta-amyloid in Alzheimer disease is controversial.
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Certain mutations can cause proteins to accumulate in neurons, leading to neurodegeneration.
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However, the role of specific HDACs in cognition and neurodegeneration remains poorly understood.
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Histopathological and radiological analysis revealed that neurodegeneration occurs early in the disease course.
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Despite extensive efforts, the precise role of a-synuclein aggregation in neurodegeneration remains unclear.
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The association with rs794185 was highly significant in the group with high neurodegeneration.
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This predicts that measures of neurodegeneration will correlate most strongly between interconnected structures.
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Recent trends demonstrate links between OSA and AD-biomarkers of neurodegeneration across all age-groups.
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The function of PERK tauopathy variants and their effects on neurodegeneration are unknown.
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This IN Tat model of neuroinflammation may be useful to study HIV-1-induced neurodegeneration.
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Both classic and milder phenotypes develop progressive neurodegeneration in early adulthood.
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Specific molecular mechanisms by which mHtt elicits neurodegeneration have been hard to determine.
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We report two sisters who presented with neurodegeneration triggered by infections.